Type I interferon as a stimulus for cross-priming

被引：105

作者：

Le Bon, Agnes ^{[1
]}

Tough, David F. ^{[2
]}

机构：

[1] INSERM, Fac Necker, AVENIR Grp, Marie Curie Excellence Team,U591, F-75015 Paris, France

[2] GlaxoSmithKline, Target Discoveruy, T Cell Regulat Grp, Stevenage SG1 2NY, Herts, England

来源：

CYTOKINE & GROWTH FACTOR REVIEWS | 2008年 / 19卷 / 01期

关键词：

IFN-alpha/beta; cross-priming; dendritic cells;

D O I：

10.1016/j.cytogfr.2007.10.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Type I interferon (IFN-alpha/beta) is induced rapidly by infection and is well recognised for its crucial role in innate defence. However, it is evident that IFN-alpha/beta also serves as a signal for the generation of adaptive immune responses. In this review, we focus on the involvement of IFN-alpha/beta in the induction of CD8(+) T cell responses by cross-priming. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：33 / 40

页数：8

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