Gold nanoparticles in delivery applications

被引：2139

作者：

Ghosh, Partha ^{[1
]}

Han, Gang ^{[1
]}

De, Mrinmoy ^{[1
]}

Kim, Chae Kyu ^{[1
]}

Rotello, Vincent M. ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2008年 / 60卷 / 11期

关键词：

gold; delivery; DNA; drug delivery; glutathione; nanoparticles; self-assembled monolayer; photochemistry; release;

D O I：

10.1016/j.addr.2008.03.016

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is their interaction with thiols, providing an effective and selective means of controlled intracellular release. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：1307 / 1315

页数：9

共 78 条

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