Phage antibacterials make a comeback

被引:30
作者
Fischetti, VA [1 ]
机构
[1] Rockefeller Univ, Lab Bacterial Pathogenesis, New York, NY 10021 USA
关键词
D O I
10.1038/90777
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Peptides derived from tiny bacterial viruses may offer an alternative strategy for combating bacterial infections.
引用
收藏
页码:734 / 735
页数:2
相关论文
共 10 条
[1]   Bacteriophage therapy and prophylaxis: Rediscovery and renewed assessment of potential [J].
Barrow, PA ;
Soothill, JS .
TRENDS IN MICROBIOLOGY, 1997, 5 (07) :268-271
[2]   The lysis protein E of φX174 is a specific inhibitor of the MraY-catalyzed step in peptidoglycan synthesis [J].
Bernhardt, TG ;
Struck, DK ;
Young, R .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (09) :6093-6097
[3]   A protein antibiotic in the phage Qβ virion:: Diversity in lysis targets [J].
Bernhardt, TG ;
Wang, IN ;
Struck, DK ;
Young, R .
SCIENCE, 2001, 292 (5525) :2326-2329
[4]   Induction of lysogenic bacteriophage and phage-associated toxin from group A streptococci during coculture with human pharyngeal cells [J].
Broudy, TB ;
Pancholi, V ;
Fischetti, VA .
INFECTION AND IMMUNITY, 2001, 69 (03) :1440-1443
[5]  
d'Herelle F, 1917, CR HEBD ACAD SCI, V165, P373
[6]   MOLECULAR EVOLUTION OF LYTIC ENZYMES OF STREPTOCOCCUS-PNEUMONIAE AND ITS BACTERIOPHAGES [J].
GARCIA, E ;
GARCIA, JL ;
GARCIA, P ;
ARRARAS, A ;
SANCHEZPUELLES, JM ;
LOPEZ, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (03) :914-918
[7]   Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme [J].
Nelson, D ;
Loomis, L ;
Fischetti, VA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (07) :4107-4112
[8]   Bacteriophage therapy [J].
Sulakvelidze, A ;
Alavidze, Z ;
Morris, JG .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :649-659
[9]   An investigation on the nature of ultra-microscopic viruses [J].
Twort, FW .
LANCET, 1915, 2 :1241-1243
[10]   Holins: The protein clocks of bacteriophage infections [J].
Wang, IN ;
Smith, DL ;
Young, R .
ANNUAL REVIEW OF MICROBIOLOGY, 2000, 54 :799-825