New types of silica-fortified magnetic nanoparticles as tools for molecular biology applications

被引:52
作者
Grüttner, C [1 ]
Teller, J [1 ]
机构
[1] Micro Caps Gmbh, D-18119 Rostock, Germany
关键词
nanoparticles; silica; dextran; zetapotential; charge density;
D O I
10.1016/S0304-8853(98)00561-7
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The synthesis and physico-chemical characterization of superparamagnetic polysaccharide nanoparticles (200-400 nm) with an iron oxide content of 75-80% are described. The robustness of the particle matrix was increased by intercalation of nanoscaled silica. Electrokinetic and streaming potential measurements have been carried out to optimize the silica content of the particles. Specific surface modifications for various in vitro particle applications can also be optimized using these measurements. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:8 / 15
页数:8
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