T cells, immunosurveillance, and cutaneous immunity

被引：7

作者：

Kupper, TS ^{[1
]}

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med,Inst Med, Skin Dis Res Ctr,Dept Dermatol, Boston, MA 02115 USA

来源：

JOURNAL OF DERMATOLOGICAL SCIENCE | 2000年 / 24卷

基金：

美国国家卫生研究院;

关键词：

immunologic memory; cell trafficking; antigen presentation; dendritic cell; T cell; autoantigen;

D O I：

10.1016/S0923-1811(00)00140-7

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

This presentation deals with the key role of the skin in immune function, briefly reviewing what is known about the cell trafficking patterns and molecular events involved in the generation of a specific immune response in the skin. Such information provides a basis for understanding the pathogenesis of autoimmunity-related diseases, and may provide clues to eventual therapeutic approaches. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：S41 / S45

页数：5

共 18 条

[1] A direct estimate of the human αβ T cell receptor diversity [J].

Arstila, TP ;

Casrouge, A ;

Baron, V ;

Even, J ;

Kanellopoulos, J ;

Kourilsky, P .

SCIENCE, 1999, 286 (5441) :958-961

[2] Dendritic cells and the control of immunity [J].

Banchereau, J ;

Steinman, RM .

NATURE, 1998, 392 (6673) :245-252

[3] Mechanisms of disease - Nuclear factor-kappa b - A pivotal transcription factor in chronic inflammatory diseases [J].

Barnes, PJ ;

Larin, M .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (15) :1066-1071

[4] Lymphocyte homing and homeostasis [J].

Butcher, EC ;

Picker, LJ .

SCIENCE, 1996, 272 (5258) :60-66

[5] Chemokines - Chemokines and cell migration in secondary lymphoid organs [J].

Cyster, JG .

SCIENCE, 1999, 286 (5447) :2098-2102

[6]

DAVIS MM, 1988, NATURE, V335, P744, DOI 10.1038/335744b0

[7] T-CELL ANTIGEN RECEPTOR GENES AND T-CELL RECOGNITION [J].

DAVIS, MM ;

BJORKMAN, PJ .

NATURE, 1988, 334 (6181) :395-402

[8] Elements of immunity - The instructive role of innate immunity in the acquired immune response [J].

Fearon, DT ;

Locksley, RM .

SCIENCE, 1996, 272 (5258) :50-54

[9] Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells [J].

Fuhlbrigge, RC ;

Kieffer, JD ;

Armerding, D ;

Kupper, TS .

NATURE, 1997, 389 (6654) :978-981

[10] Dendritic cells: Unique leukocyte populations which control the primary immune response [J].

Hart, DNJ .

BLOOD, 1997, 90 (09) :3245-3287

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