Acetylenic allenophanes:: An asymmetric synthesis of a bis(alleno)-bis(butadiynyl)-meta-cyclophane

被引：39

作者：

Clay, MD ^{[1
]}

Fallis, AG ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa, ON K1N 6N5, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 26期

关键词：

alkynes; allenes; asymmetric epoxidation; cyclophanes; diynes;

D O I：

10.1002/anie.200500484

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A cyclophane with allene and acetylene bridges has been prepared as a single enantiomer. This acetylenic allenophane (see structure) was synthesized by a series of palladium- and copper-mediated coupling reactions. The allene bridge was derived from the ring opening of a chiral epoxy alkyne, which was prepared by a Sharpless asymmetric epoxidation of an allylic alcohol. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4039 / 4042

页数：4

共 64 条

[1] PHOTOOXYGENATION OF OLEFINS IN THE PRESENCE OF TITANIUM(IV) CATALYST - A CONVENIENT ONE-POT SYNTHESIS OF EPOXY ALCOHOLS [J].