Current status of proteomic standards development

被引:25
作者
Orchard, S
Taylor, C
Hermjakob, H
Zhu, WM
Julian, RD
Apweiler, R
机构
[1] European Bioinformat Inst, Wellcome Trust, EMBL Outstn, Cambridge, England
[2] Lilly Res Labs, Indianapolis, IN 46285 USA
关键词
data standardization; mass spectrometry; protein interaction; proteomics;
D O I
10.1586/14789450.1.2.179
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The generation of proteomic data is becoming ever more high throughput. Both the technologies and experimental designs used to generate and analyze data are becoming Increasingly complex. The need for methods by which such data can be accurately described, stored and exchanged between experimenters and data repositories has been recognized. Work by the Proteome Standards Initiative of the Human Proteome Organization has laid the foundation for the development of standards by which experimental design can be described and data exchange facilitated. The Minimum Information About a Proteomic Experiment data model describes both the scope and purpose of a proteomics experiment and encompasses the development of more specific Interchange formats such as the mzData model of mass spectrometry. The eXtensible Mark-up Language-MI data interchange format, which allows exchange of molecular interaction data, has already been published and major databases within this field are supplying data downloads in this format.
引用
收藏
页码:179 / 183
页数:5
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