Chronic Obstructive Pulmonary Disease: A Concise Review

被引:38
作者
Balkissoon, Ron [1 ]
Lommatzsch, Steve [1 ]
Carolan, Brendan [1 ]
机构
[1] Natl Jewish Hlth, Div Pulm, Dept Med, Denver, CO 80206 USA
基金
美国国家卫生研究院;
关键词
Chronic obstructive pulmonary disease; Guidelines; Chronic bronchitis; Emphysema; VOLUME-REDUCTION SURGERY; METERED-DOSE INHALER; VITAMIN-D DEFICIENCY; 50; MU-G; SALMETEROL/FLUTICASONE PROPIONATE; FLUTICASONE PROPIONATE; MACROLIDE ANTIBIOTICS; SMOKING-CESSATION; TRIPLE THERAPY; LONG-TERM;
D O I
10.1016/j.mcna.2011.08.009
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Globally, chronic obstructive pulmonary disease (COPD) is a major cause of significant morbidity and mortality, and is now the third leading cause of death in the United States. Over the past 15 years there has been a surge of bench and translational research regarding the genetics and pathogenesis of COPD, and several large-scale clinical trials have introduced new treatment paradigms for COPD. Current research also demonstrates that COPD is not just a lung disease and that there are several potential extrapulmonary manifestations and comorbidities that should be evaluated and treated when one identifies an individual as having COPD.
引用
收藏
页码:1125 / +
页数:18
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