Analysis of the interaction between the transcription factor σG and the anti-sigma factor SpoIIAB of Bacillus subtilis

被引：15

作者：

Evans, L

Clarkson, J

Yudkin, MD

Errington, J

Feucht, A

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[2] Univ Oxford, Dept Biochem, Microbiol Unit, Oxford OX1 3RE, England

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 15期

关键词：

D O I：

10.1128/JB.185.15.4615-4619.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The activation of sigma(G), a transcription factor, in Bacillus subtilis is coupled to the completion of engulfment during sporulation. SpoIIAB, an anti-sigma factor involved in regulation of sigma(F), is also shown to form a complex with sigma(G) in vitro. SpoIIAA, the corresponding anti-anti-sigma factor, can disrupt the SpoIIAB:sigma(G) complex, releasing free sigma(G). The data suggest the existence of an as-yet-unknown mechanism to keep or sigma(G) inactive prior to engulfment.

引用

收藏

页码：4615 / 4619

页数：5

相关论文

共 24 条

[1] A cytoskeleton-like role for the bacterial cell wall during engulfment of the Bacillus subtilis forespore [J].

Abanes-De Mello, A ;

Sun, YL ;

Aung, S ;

Pogliano, K .

GENES & DEVELOPMENT, 2002, 16 (24) :3253-3264

[2] AN ADENOSINE NUCLEOTIDE SWITCH CONTROLLING THE ACTIVITY OF A CELL-TYPE-SPECIFIC TRANSCRIPTION FACTOR IN BACILLUS-SUBTILIS [J].

ALPER, S ;

DUNCAN, L ;

LOSICK, R .

CELL, 1994, 77 (02) :195-205

[3] BACILLUS-SUBTILIS SIGMA-B IS REGULATED BY A BINDING-PROTEIN (RSBW) THAT BLOCKS ITS ASSOCIATION WITH CORE RNA-POLYMERASE [J].

BENSON, AK ;

HALDENWANG, WG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) :2330-2334

[4] Crystal structure of the Bacillus stearothermophilus anti-σ factor SpoIIAB with the sporulation σ factor σF [J].

Campbell, EA ;

Masuda, S ;

Sun, JL ;

Muzzin, O ;

Olson, CA ;

Wang, S ;

Darst, SA .

CELL, 2002, 108 (06) :795-807

[5] ROLE OF INTERACTIONS BETWEEN SPOIIAA AND SPOIIAB IN REGULATING CELL-SPECIFIC TRANSCRIPTION FACTOR SIGMA(F) OF BACILLUS-SUBTILIS [J].

DIEDERICH, B ;

WILKINSON, JF ;

MAGNIN, T ;

NAJAFI, SMA ;

ERRINGTON, J ;

YUDKIN, MD .

GENES & DEVELOPMENT, 1994, 8 (21) :2653-2663

[6] SPOIIAB IS AN ANTI-SIGMA FACTOR THAT BINDS TO AND INHIBITS TRANSCRIPTION BY REGULATORY PROTEIN SIGMA-F FROM BACILLUS-SUBTILIS [J].

DUNCAN, L ;

LOSICK, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) :2325-2329

[7] SpoIIAA governs the release of the cell-type specific transcription factor sigma(F) from its anti-sigma factor SpoIIAB [J].

Duncan, L ;

Alper, S ;

Losick, R .

JOURNAL OF MOLECULAR BIOLOGY, 1996, 260 (02) :147-164

[8] STRUCTURE AND FUNCTION OF THE SPOIIIJ GENE OF BACILLUS-SUBTILIS - A VEGETATIVELY EXPRESSED GENE THAT IS ESSENTIAL FOR SIGMA-G ACTIVITY AT AN INTERMEDIATE STAGE OF SPORULATION [J].

ERRINGTON, J ;

APPLEBY, L ;

DANIEL, RA ;

GOODFELLOW, H ;

PARTRIDGE, SR ;

YUDKIN, MD .

JOURNAL OF GENERAL MICROBIOLOGY, 1992, 138 :2609-2618

[9] Two-stage regulation of an anti-sigma factor determines developmental fate during bacterial endospore formation [J].

Kellner, EM ;

Decatur, A ;

Moran, CP .

MOLECULAR MICROBIOLOGY, 1996, 21 (05) :913-924

[10] FORESPORE-SPECIFIC DISAPPEARANCE OF THE SIGMA-FACTOR ANTAGONIST SPOLLAB - IMPLICATIONS FOR ITS ROLE IN DETERMINATION OF CELL FATE IN BACILLUS-SUBTILIS [J].

KIRCHMAN, PA ;

DEGRAZIA, H ;

KELLNER, EM ;

MORAN, CP .

MOLECULAR MICROBIOLOGY, 1993, 8 (04) :663-671