Photoaffinity labeling of PKC isozymes by phorbol ester derivatives

被引：9

作者：

Uotsu, K ^{[1
]}

Sodeoka, M ^{[1
]}

Shibasaki, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 113, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1998年 / 6卷 / 07期

关键词：

D O I：

10.1016/S0968-0896(98)00068-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Photoaffinity probes PPDA and PPTD, which have diazoacetyl and trifluorodiazopropionyl group at C-13 position in phorbol, respectively, were synthesized. Photoaffinity labeling of protein kinase C isozymes by both the probes resulted in specific cross-linking. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1117 / 1126

页数：10

共 39 条

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