Inactivation of Ascaris suum by Short-Chain Fatty Acids

被引:32
作者
Butkus, Michael A. [2 ]
Hughes, Kelly T. [3 ]
Bowman, Dwight D. [3 ]
Liotta, Janice L. [3 ]
Jenkins, Michael B. [4 ]
Labare, Michael P. [1 ]
机构
[1] US Mil Acad, Dept Chem & Life Sci, West Point, NY 10996 USA
[2] US Mil Acad, Dept Geog & Environm Engn, West Point, NY 10996 USA
[3] Cornell Univ, Dept Microbiol & Immunol, Coll Vet Med, Ithaca, NY 14853 USA
[4] USDA ARS, Nat Resource Conservat Ctr, Watkinsville, GA 30677 USA
关键词
ORGANIC-ACIDS; TOXICITY; GROWTH; EGGS; INHIBITION; MORTALITY; OVA; PH;
D O I
10.1128/AEM.01675-10
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Ascaris suum eggs were inactivated in distilled water and digested sludge by butanoic, pentanoic, and hexanoic acids. The fatty acids (short-chain fatty acids [SCFA]) were effective only when protonated and at sufficient concentrations. The conjugate bases were not effective at the concentrations evaluated. Predictions from an inhibition model (50% inhibitory concentration [IC50]) based on quantitative structure-activity relationships were congruent with inactivation data.
引用
收藏
页码:363 / 366
页数:4
相关论文
共 23 条
[1]   UNCOUPLING BY ACETIC-ACID LIMITS GROWTH OF AND ACETOGENESIS BY CLOSTRIDIUM-THERMOACETICUM [J].
BARONOFSKY, JJ ;
SCHREURS, WJA ;
KASHKET, ER .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1984, 48 (06) :1134-1139
[2]   DETERMINING CHEMICAL TOXICITY TO AQUATIC SPECIES [J].
BLUM, DJW ;
SPEECE, RE .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1990, 24 (03) :284-293
[3]   REGULATION OF CYTOPLASMIC PH IN BACTERIA [J].
BOOTH, IR .
MICROBIOLOGICAL REVIEWS, 1985, 49 (04) :359-378
[4]   Inactivation of single-celled Ascaris suum eggs by low-pressure UV radiation [J].
Brownell, SA ;
Nelson, KL .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (03) :2178-2184
[5]   Surface properties of Ascaris suum eggs:: hydrophobic potential and Lewis acid-base interactions [J].
Capizzi, S ;
Schwartzbrod, J .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2001, 22 (02) :99-105
[6]   Liming as an advanced treatment for sludge sanitisation:: helminth eggs elimination -: Ascaris eggs as model [J].
Capizzi-Banas, S ;
Deloge, M ;
Remy, M ;
Schwartzbrod, J .
WATER RESEARCH, 2004, 38 (14-15) :3251-3258
[7]   Irradiation of Ascaris ova in sludge using an electron beam accelerator [J].
Capizzi-Banas, S ;
Schwartzbrod, J .
WATER RESEARCH, 2001, 35 (09) :2256-2260
[8]   ORGANIC-ACIDS - CHEMISTRY, ANTIBACTERIAL ACTIVITY AND PRACTICAL APPLICATIONS [J].
CHERRINGTON, CA ;
HINTON, M ;
MEAD, GC ;
CHOPRA, I .
ADVANCES IN MICROBIAL PHYSIOLOGY, 1991, 32 :87-108
[9]   INHIBITION OF ESCHERICHIA-COLI K12 BY SHORT-CHAIN ORGANIC-ACIDS - LACK OF EVIDENCE FOR INDUCTION OF THE SOS RESPONSE [J].
CHERRINGTON, CA ;
HINTON, M ;
PEARSON, GR ;
CHOPRA, I .
JOURNAL OF APPLIED BACTERIOLOGY, 1991, 70 (02) :156-160
[10]   Inactivation of Ascaris suum in a biodrying compost system [J].
Collick, Amy S. ;
Inglis, Scott ;
Wright, Peter ;
Steenhuis, Tammo S. ;
Bowman, Dwight D. .
JOURNAL OF ENVIRONMENTAL QUALITY, 2007, 36 (05) :1528-1533