Nomenclature of monocytes and dendritic cells in blood

被引：1862

作者：

Ziegler-Heitbrock, Loems ^{[1
,2
]}

Ancuta, Petronela ^{[3
,4
]}

Crowe, Suzanne ^{[5
]}

Dalod, Marc ^{[6
,7
,8
]}

Grau, Veronika ^{[9
]}

Hart, Derek N. ^{[10
]}

Leenen, Pieter J. M. ^{[11
]}

Liu, Yong-Jun ^{[12
]}

MacPherson, Gordon ^{[13
]}

Randolph, Gwendalyn J. ^{[14
]}

Scherberich, Juergen ^{[15
]}

Schmitz, Juergen ^{[16
]}

Shortman, Ken ^{[17
]}

Sozzani, Silvano ^{[18
]}

Strobl, Herbert ^{[19
]}

Zembala, Marek ^{[20
]}

Austyn, Jonathan M. ^{[21
]}

Lutz, Manfred B. ^{[22
]}

机构：

[1] Helmholtz Zentrum Munchen, D-82131 Gauting, Germany

[2] Univ Leicester, Dept Infect Immun & Inflammat, Leicester, Leics, England

[3] Univ Montreal, CHUM, Montreal, PQ, Canada

[4] INSERM, U743, Montreal, PQ, Canada

[5] Macfarlane Burnet Inst Med Res, Melbourne, Vic, Australia

[6] Univ Mediterranee, CIML, Marseille, France

[7] INSERM, U631, F-13258 Marseille, France

[8] CNRS, UMR 6102, Marseille, France

[9] Univ Giessen, Expt Surg Lab, Dept Gen & Thorac Surg, Giessen, Germany

[10] Anzac Res Inst, Sydney, NSW, Australia

[11] Erasmus MC, Dept Immunol, Rotterdam, Netherlands

[12] Univ Texas MD Anderson Canc Ctr, Dept Immunol, Houston, TX 77030 USA

[13] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[14] Mt Sinai Sch Med, New York, NY USA

[15] Univ Munich, Municipal Hosp Harlaching, Klin Nephrol & Klin Immunol, Munich, Germany

[16] Miltenyi Biotec, Dept Res & Dev, Bergisch Gladbach, Germany

[17] Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia

[18] Univ Brescia, Dept Biomed Sci & Biotechnol, Brescia, Italy

[19] Med Univ Vienna, Inst Immunol, Vienna, Austria

[20] Jagiellonian Univ Med Coll, Polish Amer Inst Paediat, Dept Clin Immunol, Krakow, Poland

[21] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg, Oxford OX3 9DU, England

[22] Univ Wurzburg, Inst Virol & Immunobiol, Wurzburg, Germany

来源：

BLOOD | 2010年 / 116卷 / 16期

关键词：

HUMAN PERIPHERAL-BLOOD; COLONY-STIMULATING FACTOR; IN-VIVO; LYMPH-NODES; MONONUCLEAR PHAGOCYTES; MOUSE-BLOOD; SUBSETS; DISTINCT; IDENTIFICATION; EXPRESSION;

D O I：

10.1182/blood-2010-02-258558

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community. (Blood.2010;116(16):e74-e80)

引用

页码：E74 / E80

页数：7

共 63 条

[1] IDENTIFICATION OF 2 SUBPOPULATIONS OF RAT MONOCYTES EXPRESSING DISPARATE MOLECULAR-FORMS AND QUANTITIES OF CD43 [J].

AHUJA, V ;

MILLER, SE ;

HOWELL, DN .

CELLULAR IMMUNOLOGY, 1995, 163 (01) :59-69

[2] Fractalkine preferentially mediates arrest and migration of CD16+ monocytes [J].

Ancuta, P ;

Rao, R ;

Moses, A ;

Mehle, A ;

Shaw, SK ;

Luscinskas, FW ;

Gabuzda, D .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (12) :1701-1707

[3] Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+and CD16-monocyte subsets [J].

Ancuta, Petronela ;

Liu, Kuang-Yu ;

Misra, Vikas ;

Wacleche, Vanessa Sue ;

Gosselin, Annie ;

Zhou, Xiaobo ;

Gabuzda, Dana .

BMC GENOMICS, 2009, 10 :403

[4] Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody [J].

Asselin-Paturel, C ;

Brizard, G ;

Pin, JJ ;

Brière, F ;

Trinchieri, G .

JOURNAL OF IMMUNOLOGY, 2003, 171 (12) :6466-6477

[5] The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF [J].

Belge, KU ;

Dayyani, F ;

Horelt, A ;

Siedlar, M ;

Frankenberger, M ;

Frankenberger, B ;

Espevik, T ;

Ziegler-Heitbrock, L .

JOURNAL OF IMMUNOLOGY, 2002, 168 (07) :3536-3542

[6] Bone marrow stromal cell antigen 2 is a specific marker of type IIFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation [J].

Blasius, Amanda L. ;

Giurisato, Emanuele ;

Celia, Marina ;

Schreiber, Robert D. ;

Shaw, Andrey S. ;

Colonna, Marco .

JOURNAL OF IMMUNOLOGY, 2006, 177 (05) :3260-3265

[7] Increased TNF expression in CD43++ murine blood monocytes [J].

Burke, Bernard ;

Ahmad, Rasheedah ;

Staples, Karl J. ;

Snowden, Roger ;

Kadioglu, Aras ;

Frankenberger, Marion ;

Hume, David A. ;

Ziegler-Heitbrock, Loems .

IMMUNOLOGY LETTERS, 2008, 118 (02) :142-147

[8] The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement [J].

Caminschi, Irina ;

Proietto, Anna I. ;

Ahmet, Fatma ;

Kitsoulis, Susie ;

Teh, Joo Shin ;

Lo, Jennifer C. Y. ;

Rizzitelli, Alexandra ;

Wu, Li ;

Vremec, David ;

van Dommelen, Serani L. H. ;

Campbell, Ian K. ;

Maraskovsky, Eugene ;

Braley, Hal ;

Davey, Gayle M. ;

Mottram, Patricia ;

De Velde, Nicholas van ;

Jensen, Kent ;

Lew, Andrew M. ;

Wright, Mark D. ;

Heath, William R. ;

Shortman, Ken ;

Lahoud, Mireille H. .

BLOOD, 2008, 112 (08) :3264-3273

[9] Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon [J].

Cella, M ;

Jarrossay, D ;

Facchetti, F ;

Alebardi, O ;

Nakajima, H ;

Lanzavecchia, A ;

Colonna, M .

NATURE MEDICINE, 1999, 5 (08) :919-923

[10] The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells [J].

Crozat, Karine ;

Guiton, Rachel ;

Contreras, Vanessa ;

Feuillet, Vincent ;

Dutertre, Charles-Antoine ;

Ventre, Erwan ;

Manh, Thien-Phong Vu ;

Baranek, Thomas ;

Storset, Anne K. ;

Marvel, Jacqueline ;

Boudinot, Pierre ;

Hosmalin, Anne ;

Schwartz-Cornil, Isabelle ;

Dalod, Marc .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (06) :1283-1292

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