Induced hypothermia in adult community-acquired bacterial meningitis - more than just a possibility?

被引:19
作者
Lepur, Dragan [1 ]
Kutlesa, Marko [1 ]
Barsic, Bruno [1 ]
机构
[1] Univ Zagreb, Univ Hosp Infect Dis Dr Fran Mihaljevic, Dept Neuroinfect & Intens Care Med, HR-10002 Zagreb, Croatia
关键词
Hypothermia; Adult; Community-acquired; Bacterial meningitis; S; pneumoniae; MILD HYPOTHERMIA; MENINGOCOCCAL MENINGITIS; THERAPEUTIC HYPOTHERMIA; EMERGENCY HYPOTHERMIA; MODERATE HYPOTHERMIA; COMPLICATIONS; PRESSURE; FUTURE; INJURY; BRAIN;
D O I
10.1016/j.jinf.2010.10.001
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We present the case series of adult community-acquired bacterial meningitis treated with hypothermia. The major criteria for therapeutic hypothermia (TH) was impaired carbon dioxide reactivity (CO2R) assessed by Transcranial Doppler (TCD). In patients without temporal acoustic window, minor criteria (optic nerve sheath diameter >= 6.0 mm plus GCS <= 8) were required. According to our, although limited experience, the use of mild hypothermia in selected patients with community-acquired bacterial meningitis accompanied with appropriate monitoring could be a promising treatment tool. (C) 2010 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:172 / 177
页数:6
相关论文
共 27 条
[1]   Effect of moderate hypothermia on systemic and internal jugular plasma IL-6 levels after traumatic brain injury in humans [J].
Aibiki, M ;
Maekawa, S ;
Ogura, S ;
Kinoshita, Y ;
Kawai, N ;
Yokono, S .
JOURNAL OF NEUROTRAUMA, 1999, 16 (03) :225-232
[2]   EFFECT OF MILD HYPOTHERMIA ON ISCHEMIA-INDUCED RELEASE OF NEUROTRANSMITTERS AND FREE FATTY-ACIDS IN RAT-BRAIN [J].
BUSTO, R ;
GLOBUS, MY ;
DIETRICH, WD ;
MARTINEZ, E ;
VALDES, I ;
GINSBERG, MD .
STROKE, 1989, 20 (07) :904-910
[3]   Management of bacterial meningitis in adults - Algorithm from the British Infection Society represents current standard of care [J].
Cohen, J .
BMJ-BRITISH MEDICAL JOURNAL, 2003, 326 (7397) :996-997
[4]   Intracranial pressure measurement, induced hypothermia and barbiturate coma in meningitis associated with intractable raised intracranial pressure [J].
Cuthbertson, BH ;
Dickson, R ;
Mackenzie, A .
ANAESTHESIA, 2004, 59 (09) :908-911
[5]   Dexamethasone in adults with bacterial meningitis. [J].
de Gans, J ;
van de Beek, D .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (20) :1549-1556
[6]   Validation of the optic nerve sheath response to changing cerebrospinal fluid pressure: Ultrasound findings during intrathecal infusion tests [J].
Hansen, HC ;
Helmke, K .
JOURNAL OF NEUROSURGERY, 1997, 87 (01) :34-40
[7]   Hypothermia as an adjunctive treatment for severe bacterial meningitis [J].
Irazuzta, JE ;
Pretzlaff, R ;
Rowin, M ;
Milam, K ;
Zemlan, FP ;
Zingarelli, B .
BRAIN RESEARCH, 2000, 881 (01) :88-97
[8]   Modulation of nuclear factor-κB activation and decreased markers of neurological injury associated with hypothermic therapy in experimental bacterial meningitis [J].
Irazuzta, JE ;
Pretzlaff, RK ;
Zingarelli, B ;
Xue, V ;
Zemlan, F .
CRITICAL CARE MEDICINE, 2002, 30 (11) :2553-2559
[9]   Moderate hypothermia delays proinflammatory cytokine production of human peripheral blood mononuclear cells [J].
Kimura, A ;
Sakurada, S ;
Ohkuni, H ;
Todome, Y ;
Kurata, K .
CRITICAL CARE MEDICINE, 2002, 30 (07) :1499-1502
[10]   Pathogenesis and pathophysiology of pneumococcal meningitis [J].
Koedel, U ;
Scheld, WM ;
Pfister, HW .
LANCET INFECTIOUS DISEASES, 2002, 2 (12) :721-736