Is Escherichia coli getting old?

被引:14
作者
Woldringh, CL [1 ]
机构
[1] Univ Amsterdam, Bioctr Amsterdam, Swammerdam Inst Life Sci, Sect Mol Cytol, NL-1098 SM Amsterdam, Netherlands
关键词
D O I
10.1002/bies.20271
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Whether or not bacteria divide symmetrically, the inheritance of cell poles is always asymmetrical. Because each cell carries an old and a new pole, its daughters will not be the same. Tracking poles of cells and measuring their lengths and doubling times in micro-colonies, Stewart et al.((1)) observed that growth rate diminished in cells inheriting old poles and concluded that these cells are susceptible to aging. Here, their results are compared with studies on the variabilities of length and age at division. It is argued that the decreased growth rate in old pole cells falls within the expected variation and may therefore be sufficiently far from a catastrophe-like cell death through aging.
引用
收藏
页码:770 / 774
页数:5
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