The epidemiology and global burden of autism spectrum disorders

被引:737
作者
Baxter, A. J. [1 ,2 ]
Brugha, T. S. [3 ]
Erskine, H. E. [1 ,2 ]
Scheurer, R. W. [2 ]
Vos, T. [1 ,4 ]
Scott, J. G. [2 ,5 ,6 ]
机构
[1] Univ Queensland, Sch Populat Hlth, Herston, Qld, Australia
[2] Queensland Ctr Mental Hlth Res, Wacol, Australia
[3] Univ Leicester, Leicester Gen Hosp, Dept Hlth Sci, Leicester LE1 7RH, Leics, England
[4] Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA
[5] Univ Queensland, Clin Res Ctr, Herston, Qld, Australia
[6] Royal Brisbane & Womens Hosp, Herston, Qld, Australia
基金
比尔及梅琳达.盖茨基金会;
关键词
Asperger's disorder; autism; autistic spectrum disorders; burden of disease; epidemiological study; epidemiology; global health; mental disorders; prevalence; public health; PERVASIVE DEVELOPMENTAL DISORDERS; ET-AL; 2002; CHANGING PREVALENCE; PRESCHOOL-CHILDREN; ASPERGER-SYNDROME; DISEASE; BLAXILL; SPITZER; BASKIN; COMMON;
D O I
10.1017/S003329171400172X
中图分类号
B849 [应用心理学];
学科分类号
040203 [应用心理学];
摘要
Background. Autism spectrum disorders (ASDs) are persistent disabling neurodevelopmental disorders clinically evident from early childhood. For the first time, the burden of ASDs has been estimated for the Global Burden of Disease Study 2010 (GBD 2010). The aims of this study were to develop global and regional prevalence models and estimate the global burden of disease of ASDs. Method. A systematic review was conducted for epidemiological data (prevalence, incidence, remission and mortality risk) of autistic disorder and other ASDs. Data were pooled using a Bayesian meta-regression approach while adjusting for between-study variance to derive prevalence models. Burden was calculated in terms of years lived with disability (YLDs) and disability-adjusted life-years (DALYs), which are reported here by world region for 1990 and 2010. Results. In 2010 there were an estimated 52 million cases of ASDs, equating to a prevalence of 7.6 per 1000 or one in 132 persons. After accounting for methodological variations, there was no clear evidence of a change in prevalence for autistic disorder or other ASDs between 1990 and 2010. Worldwide, there was little regional variation in the prevalence of ASDs. Globally, autistic disorders accounted for more than 58 DALYs per 100000 population and other ASDs accounted for 53 DALYs per 100000. Conclusions. ASDs account for substantial health loss across the lifespan. Understanding the burden of ASDs is essential for effective policy making. An accurate epidemiological description of ASDs is needed to inform public health policy and to plan for education, housing and financial support services.
引用
收藏
页码:601 / 613
页数:13
相关论文
共 51 条
[1]
[Anonymous], J ENV IMMUNOL TOXICO
[2]
[Anonymous], 2009, AUTISM SPECTRUM DISO
[3]
[Anonymous], 2009, Time
[4]
[Anonymous], 1993, WORLD DEV REPORT 199
[5]
[Anonymous], 1994, AM PSYCHIATR ASSOC
[6]
APA, 2013, DESK REF DIAGN CRIT
[7]
APA A.P. A., 2000, Diagnostic and statistical manual of mental disorders: DSM-IV, V4th
[8]
Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP) [J].
Baird, Gillian ;
Simonoff, Emily ;
Pickles, Andrew ;
Chandler, Susie ;
Loucas, Tom ;
Meldrum, David ;
Charman, Tony .
LANCET, 2006, 368 (9531) :210-215
[9]
Global Epidemiology of Mental Disorders: What Are We Missing? [J].
Baxter, Amanda J. ;
Patton, George ;
Scott, Kate M. ;
Degenhardt, Louisa ;
Whiteford, Harvey A. .
PLOS ONE, 2013, 8 (06)
[10]
Autism after adolescence: Population-based 13- to 22-year follow-up study of 120 individuals with autism diagnosed in childhood [J].
Billstedt, E ;
Gillberg, C ;
Gillberg, C .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2005, 35 (03) :351-360