Fumarate: Multiple functions of a simple metabolite

被引：72

作者：

Araujo, Wagner L. ^{[1
]}

Nunes-Nesi, Adriano ^{[1
,2
]}

Fernie, Alisdair R. ^{[1
]}

机构：

[1] Max Planck Inst Mol Pflanzenphysiol, D-14476 Potsdam, Germany

[2] Univ Fed Vicosa, Dept Biol Vegetal, BR-36570000 Vicosa, MG, Brazil

来源：

PHYTOCHEMISTRY | 2011年 / 72卷 / 09期

关键词：

Fumarate; Mitochondrial metabolism; Tricarboxylic acid cycle; Metabolism; Stomatal function; ELECTRON-TRANSFER FLAVOPROTEIN; ORYZAE FERMENTATION EXTRACT; GAMMA-AMINOBUTYRATE SHUNT; ORGANIC-ACID METABOLISM; MALATE-DEHYDROGENASE; ESCHERICHIA-COLI; YEAST FUMARASE; AMINO-ACID; NITRATE ASSIMILATION; STOMATAL RESPONSES;

D O I：

10.1016/j.phytochem.2011.02.028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although much is now known about fumarate metabolism, our knowledge of some aspects of its biological function remain far from comprehensive. In this short review we begin with an introductory overview of the role of fumarate in both plant and non-plant systems. We next highlight the relative importance of fumarate in relation to cell type and circumstance in contrast to other chemically similar organic acids. Considerable cumulative evidence is suggestive of a role for fumarate in pH regulation during nitrate assimilation and that fumarate has similar effects as malate during stomatal movement. Indeed it is currently difficult to separate the biological function of fumarate from malate under certain circumstances. However, in other cases this can be easily performed. This physiological complexity notwithstanding it remains possible that the engineering of fumarate metabolism may provide opportunities to improve plant growth and performance. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：838 / 843

页数：6

共 96 条

[1] INTRACELLULAR-DISTRIBUTION OF FUMARASE IN VARIOUS ANIMALS [J].

AKIBA, T ;

HIRAGA, K ;

TUBOI, S .

JOURNAL OF BIOCHEMISTRY, 1984, 96 (01) :189-195

[2] A seed high-lysine trait is negatively associated with the TCA cycle and slows down Arabidopsis seed germination [J].

Angelovici, Ruthie ;

Fait, Aaron ;

Fernie, Alisdair R. ;

Galili, Gad .

NEW PHYTOLOGIST, 2011, 189 (01) :148-159

[3] Identification of the 2-Hydroxyglutarate and Isovaleryl-CoA Dehydrogenases as Alternative Electron Donors Linking Lysine Catabolism to the Electron Transport Chain of Arabidopsis Mitochondria [J].

Araujo, Wagner L. ;

Ishizaki, Kimitsune ;

Nunes-Nesi, Adriano ;

Larson, Tony R. ;

Tohge, Takayuki ;

Krahnert, Ina ;

Witt, Sandra ;

Obata, Toshihiro ;

Schauer, Nicolas ;

Graham, Ian A. ;

Leaver, Christopher J. ;

Fernie, Alisdair R. .

PLANT CELL, 2010, 22 (05) :1549-1563

[4]

ARAUJO WL, 2011, PLANT CELL

[5] The role of root exudates in rhizosphere interations with plants and other organisms [J].

Bais, Harsh P. ;

Weir, Tiffany L. ;

Perry, Laura G. ;

Gilroy, Simon ;

Vivanco, Jorge M. .

ANNUAL REVIEW OF PLANT BIOLOGY, 2006, 57 :233-266

[6] Allelopathy and exotic plant invasion: From molecules and genes to species interactions [J].

Bais, HP ;

Vepachedu, R ;

Gilroy, S ;

Callaway, RM ;

Vivanco, JM .

SCIENCE, 2003, 301 (5638) :1377-1380

[7] Root specific elicitation and antimicrobial activity of rosmarinic acid in hairy root cultures of Ocimum basilicum [J].

Bais, HP ;

Walker, TS ;

Schweizer, HP ;

Vivanco, JA .

PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2002, 40 (11) :983-995

[8] FUMARATE OR A FUMARATE METABOLITE RESTORES SWITCHING ABILITY TO ROTATING FLAGELLA OF BACTERIAL ENVELOPES [J].

BARAK, R ;

EISENBACH, M .

JOURNAL OF BACTERIOLOGY, 1992, 174 (02) :643-645

[9] Mitochondrial succinic-semialdehyde dehydrogenase of the γ-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants [J].

Bouché, N ;

Fait, A ;

Bouchez, D ;

Moller, SG ;

Fromm, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (11) :6843-6848

[10]

Callaway TR, 1996, J ANIM SCI, V74, P1982

← 1 2 3 4 5 6 7 8 9 10 →