A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy-olefin cyclisation

被引：16

作者：

Aggarwal, VK ^{[1
]}

Bethel, PA

Giles, R

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

[2] SmithKline Beecham, Tonbridge TN11 9AN, Kent, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 04期

关键词：

D O I：

10.1039/a808644c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bicyclic ester 2, a key intermediate in the first total synthesis of (+)-pyripyropene A 1, was synthesised from geraniol in 11 steps, utilising an epoxy-olefin biomimetic cyclisation as the key step.

引用

页码：325 / 326

页数：2

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