The acute effect of Swedish-style snus on cigarette craving and self-administration in male and female smokers

被引:10
作者
Barrett, Sean P. [1 ]
Campbell, Mallory L.
Temporale, Kirsten
Good, Kim Berley P.
机构
[1] Dalhousie Univ, Dept Psychol, Halifax, NS B3H 4J1, Canada
关键词
smoking; craving; snus; self-administration; tobacco; nicotine; NICOTINE; SMOKING; TOBACCO; INITIATION; CESSATION;
D O I
10.1002/hup.1170
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction Swedish-style snus (SS) has recently garnered controversy for its proposed use as a smoking cessation aid and/or harm reduction tool. However, to date, little work has been done to evaluate the extent to which SS affects cigarette cravings and smoking behavior under double-blind controlled conditions. Methods During four double-blind placebo-controlled randomized sessions, 15 smokers (8 male) administered SS, placebo (nicotine/tobacco-free) snus (PS), a nicotine-containing lozenge (NL), or a placebo lozenge (PL) for 30 min and assessed their effects using Visual Analogue Scales and the Brief Questionnaire of Smoking Urges. They could then self-administer their usual brand of cigarettes using a progressive ratio task over the next 60 min. Following the completion of their final session, 11 participants (6 male) ranked each of the products used in the study in terms of their preferences. Results Relative to the other products, SS was associated with a decreased intention to smoke as well as a delayed onset of cigarette smoking in men but not women. However, SS administration was also associated with increased feelings of frustration and irritability relative to NL and SS was ranked as being the least preferred product used in the study. Discussion Findings suggest that SS is effective in acutely suppressing craving and smoking in at least some smokers, but that its acceptability may be limited. Copyright (C) 2011 John Wiley & Sons, Ltd.
引用
收藏
页码:58 / 62
页数:5
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