EcoCyc: An encyclopedia of Escherichia coli genes and metabolism

被引：79

作者：

Karp, PD ^{[1
]}

Riley, M ^{[1
]}

Paley, SM ^{[1
]}

PelligriniToole, A ^{[1
]}

机构：

[1] MARINE BIOL LAB, WOODS HOLE, MA 02543 USA

来源：

NUCLEIC ACIDS RESEARCH | 1996年 / 24卷 / 01期

关键词：

D O I：

10.1093/nar/24.1.32

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The encyclopedia of Escherichia coli genes and metabolism (EcoCyc) is a database that combines information about the genome and the intermediary metabolism of E.coli. It describes 2034 genes, 306 enzymes encoded by these genes, 580 metabolic reactions that occur in E.coli and the organization of these reactions into 100 metabolic pathways. The EcoCyc graphical user interface allows query and exploration of the EcoCyc database using visualization tools such as genomic map browsers and automatic layouts of metabolic pathways. EcoCyc spans the space from sequence to function to allow investigation of an unusually broad range of questions. EcoCyc can be thought of as both an electronic review article, because of its copious references to the primary literature, and as an in silico model of E.coli that can be probed and analyzed through computational means.

引用

页码：32 / 39

页数：8

共 17 条

[1]

[Anonymous], 1992, ENZYME NOMENCLATURE

[2] THE ENZYME DATA-BANK [J].

BAIROCH, A .

NUCLEIC ACIDS RESEARCH, 1994, 22 (17) :3626-3627

[3]

INGRAHAM J, 1987, ESHERICHIA COLI SALM, V1

[4]

INGRAHAM J, 1987, ESHERICHIA COLI SALM, V2

[5]

KARP P, 1994, 2ND P INT C INT SYST, P203

[6]

KARP P, 1993, ADV COMPUTER METHODS, P560

[7]

KARP P, 1994, 3RD P INT C BIOINF G

[8]

KARP P, 1993, 1ST P INT C INT SYST, P207

[9] REPRESENTING, ANALYZING, AND SYNTHESIZING BIOCHEMICAL PATHWAYS [J].

KARP, PD ;

MAVROVOUNIOTIS, ML .

IEEE EXPERT-INTELLIGENT SYSTEMS & THEIR APPLICATIONS, 1994, 9 (02) :11-21

[10]

KARP PD, 1992, COMPUT APPL BIOSCI, V8, P347

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