Hydrogenosomes, mitochondria and early eukaryotic evolution

被引:102
作者
Embley, TM [1 ]
van der Giezen, M [1 ]
Horner, DS [1 ]
Dyal, PL [1 ]
Bell, S [1 ]
Foster, PG [1 ]
机构
[1] Nat Hist Museum, Dept Zool, London SW7 5BD, England
关键词
hydrogenosomes; mitochondria; hydrogenase; early eukaryotes; organelles; evolution;
D O I
10.1080/15216540310001592834
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Available data suggest that unusual organelles called hydrogenosomes, that make ATP and hydrogen, and which are found in diverse anaerobic eukaryotes, were once mitochondria. The evolutionary origins of the enzymes used to make hydrogen, pyruvate: ferredoxin oxidoreductase (PFO) and hydrogenase, are unresolved, but it seems likely that both were present at an early stage of eukaryotic evolution. Once thought to be restricted to a few unusual anaerobes, these proteins are found in diverse eukaryotic cells, including our own, where they are targeted to different cell compartments. Organelles related to mitochondria and hydrogenosomes have now been found in species of anaerobic and parasitic protozoa that were previously thought to have separated from other eukaryotes before the mitochondrial endosymbiosis. Thus it is possible that all eukaryotes may eventually be shown to contain an organelle of mitochondrial ancestry, bearing testimony to the important role that the mitochondrial endosymbiosis has played in eukaryotic evolution. It remains to be seen if members of this family of organelles share a common function essential to the eukaryotic cell, that provides the underlying selection pressure for organelle retention under different living conditions.
引用
收藏
页码:387 / 395
页数:9
相关论文
共 38 条
  • [1] A hydrogenosome with a genome
    Akhmanova, A
    Voncken, F
    van Alen, T
    van Hoek, A
    Boxma, B
    Vogels, G
    Veenhuiss, M
    Hackstein, JHP
    [J]. NATURE, 1998, 396 (6711) : 527 - 528
  • [2] Prenylated prelamin A interacts with Narf, a novel nuclear protein
    Barton, RM
    Worman, HJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (42) : 30008 - 30018
  • [3] Identification and characterization of [Fe]-hydrogenases in the hydrogenosome of Trichomonas vaginalis
    Bui, ETN
    Johnson, PJ
    [J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1996, 76 (1-2) : 305 - 310
  • [4] A common evolutionary origin for mitochondria and hydrogenosomes
    Bui, ETN
    Bradley, PJ
    Johnson, PJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) : 9651 - 9656
  • [5] An [Fe] hydrogenase from the anaerobic hydrogenosome-containing fungus Neocallimastix frontalis L2
    Davidson, EA
    van der Giezen, M
    Horner, DS
    Embley, TM
    Howe, CJ
    [J]. GENE, 2002, 296 (1-2) : 45 - 52
  • [6] Origins of hydrogenosomes and mitochondria: evolution and organelle biogenesis
    Dyall, SD
    Johnson, PJ
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2000, 3 (04) : 404 - 411
  • [7] Presence of a member of the mitochondrial carrier family in hydrogenosomes:: Conservation of membrane-targeting pathways between hydrogenosomes and mitochondria
    Dyall, SD
    Koehler, CM
    Delgadillo-Correa, MG
    Bradley, PJ
    Plümper, E
    Leuenberger, D
    Turck, CW
    Johnson, PJ
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (07) : 2488 - 2497
  • [8] THE USE OF SMALL-SUBUNIT RIBOSOMAL-RNA SEQUENCES TO UNRAVEL THE RELATIONSHIPS BETWEEN ANAEROBIC CILIATES AND THEIR METHANOGEN ENDOSYMBIONTS
    EMBLEY, TM
    FINLAY, BJ
    [J]. MICROBIOLOGY-SGM, 1994, 140 : 225 - 235
  • [9] Mitochondria and hydrogenosomes are two forms of the same fundamental organelle
    Embley, TM
    van der Giezen, M
    Horner, DS
    Dyal, PL
    Foster, P
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2003, 358 (1429) : 191 - 202
  • [10] Anaerobic eukaryote evolution: hydrogenosomes as biochemically modified mitochondria?
    Embley, TM
    Horner, DA
    Hirt, RP
    [J]. TRENDS IN ECOLOGY & EVOLUTION, 1997, 12 (11) : 437 - 441