Tenofovir and emtricitabine cerebrospinal fluid-to-plasma ratios correlate to the extent of blood-brainbarrier damage

被引：24

作者：

Calcagno, Andrea ^{[1
]}

Bonora, Stefano ^{[1
]}

Simiele, Marco ^{[2
]}

Rostagno, Roberto ^{[1
]}

Tettoni, Maria C. ^{[1
]}

Bonasso, Marino ^{[1
]}

Romito, Alessandra ^{[3
]}

Imperiale, Daniele ^{[4
]}

D'Avolio, Antonio ^{[2
]}

Di Perri, Giovanni ^{[1
]}

机构：

[1] Univ Turin, Dept Infect Dis, Turin, Italy

[2] Univ Turin, Pharmacokinet & Pharmacogenet Lab, Turin, Italy

[3] Maria Vittoria Hosp, Lab Immunool, Turin, Italy

[4] Maria Vittoria Hosp, Dept Neurol, Turin, Italy

来源：

AIDS | 2011年 / 25卷 / 11期

关键词：

D O I：

10.1097/QAD.0b013e3283489cb1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1437 / 1439

页数：3

共 10 条

[1] Effects of antiretroviral treatment on blood-brain barrier integrity and intrathecal immunoglobulin production in neuroasymptomatic HIV-1-infected patients [J].

Abdulle, S ;

Hagberg, L ;

Gisslén, M .

HIV MEDICINE, 2005, 6 (03) :164-169

[2]

BEST B, 2009, 16 C RETR OPP INF, P702

[3]

BEST B, 2008, 15 C RETR OPP INF BO, P131

[4] Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral Therapy [J].

Canestri, Ana ;

Lescure, Francois-Xavier ;

Jaureguiberry, Stephane ;

Moulignier, Antoine ;

Amiel, Corinne ;

Marcelin, Anne Genevieve ;

Peytavin, Gilles ;

Tubiana, Roland ;

Pialoux, Gilles ;

Katlama, Christine .

CLINICAL INFECTIOUS DISEASES, 2010, 50 (05) :773-778

[5] A new assay based on solid-phase extraction procedure with LC-MS to measure plasmatic concentrations of tenofovir and emtricitabine in HIV infected patients [J].

D'Avolio, Antonio ;

Sciandra, Mauro ;

Siccardi, Marco ;

Baietto, Lorena ;

de Requena, Daniel Gonzalez ;

Bonora, Stefano ;

Di Perri, Giovanni .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2008, 46 (06) :524-528

[6] Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis [J].

Dallasta, LM ;

Pisarov, LA ;

Esplen, JE ;

Werley, JV ;

Moses, AV ;

Nelson, JA ;

Achim, CL .

AMERICAN JOURNAL OF PATHOLOGY, 1999, 155 (06) :1915-1927

[7]

Letendre S, 2010, 17 C RETR OPP INF SA, P430

[8]

LETENDRE S, 2011, 18 C RETR OPP INF BO, P408

[9] Blood-brain barrier damage and brain penetration of antiepileptic drugs: Role of serum proteins and brain edema [J].

Marchi, Nicola ;

Betto, Giulia ;

Fazio, Vincent ;

Fan, Quinyuan ;

Ghosh, Chaitali ;

Machado, Andre ;

Janigro, Damir .

EPILEPSIA, 2009, 50 (04) :664-677

[10] Raltegravir Cerebrospinal Fluid Concentrations in HIV-1 Infection [J].

Yilmaz, Aylin ;

Gisslen, Magnus ;

Spudich, Serena ;

Lee, Evelyn ;

Jayewardene, Anura ;

Aweeka, Francesca ;

Price, Richard W. .

PLOS ONE, 2009, 4 (09)

← 1 →