Extended scope of in situ iodotrimethylsilane mediated selective reduction of benzylic alcohols

被引：19

作者：

Cain, GA ^{[1
]}

Holler, ER ^{[1
]}

机构：

[1] DuPont Pharmaceut Co, Expt Stn E336109, Wilmington, DE 19805 USA

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 13期

关键词：

D O I：

10.1039/b102495g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iodotrimethylsilane, generated in situ from chlorotrimethylsilane and sodium iodide in acetonitrile, selectively reduces moderately electron deficient benzylic alcohols to the analogous toluenes; other reduction sensitive functional groups such as ketone, aldehyde, nitrile, and nitro are unaffected.

引用

页码：1168 / 1169

页数：2

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