The use of glycol ethers has changed significantly over the past 30 years. Low molecular weight E-series have been phased-out and progressively replaced by low molecular weight P-series whenever possible. There is a trend to shift from E-series to P-series and an obvious willingness to Substitute where alternative solutions exist or as a consequence of strengthening regulation and voluntary measures to reduce exposure in the workplace. (C) 2004 Elsevier Ireland Ltd. All rights reserved.