Direct diastereoselective synthesis of (±)-cis- and (±)-trans-4-methylpipecolic acid and derivatives

被引：13

作者：

Cossy, J ^{[1
]}

Belotti, D ^{[1
]}

机构：

[1] ESPCI, CNRS, Chim Organ Lab, F-75231 Paris 05, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 11期

关键词：

piperidine; pipecolic acid; electrophile; 4-methylpipecolic acid;

D O I：

10.1016/S0040-4039(01)00138-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(+/-)-cis- or (+/-)-trans-4-Methylpipecolic acid and ester derivatives can be obtained directly by addition of electrophiles to alpha -lithiated N-Boc 4-methylpiperidine. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2119 / 2120

页数：2

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