Influence of Th1, Th2, and Th3 cytokines during the early phase after liver transplantation

被引：18

作者：

Wang, YI ^{[1
]}

Tang, ZQ ^{[1
]}

Gao, W ^{[1
]}

Jiang, Y ^{[1
]}

Zhang, XH ^{[1
]}

Peng, L ^{[1
]}

机构：

[1] First Cent Hosp, Organ Transplantat Ctr Tianjin, Tianjin Inst Thrombosis & Hemostasis, Tianjin, Peoples R China

来源：

TRANSPLANTATION PROCEEDINGS | 2003年 / 35卷 / 08期

关键词：

D O I：

10.1016/j.transproceed.2003.10.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To investigate the change of Th1, Th2, Th3 cytokines during early liver transplantation. IFN-r, IL-4, TGF-beta production by CD4(+) T cells were determined by fluorescence activated cell sorter analysis. Comparing the acute rejection with the non-acute rejection groups on the 7th, 14th, and 28th day showed that high interferon-gamma production associated with acute rejection in the early posttransplant period. There was no evidence of significant changes in interleukin-4 and transforming growth factor beta (TGF-beta) levels between non-acute rejection groups with acute rejection groups. Th1 cytokine high production is significantly associated with acute rejection in liver transplant recipients.

引用

页码：3024 / 3025

页数：2

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