New Method for the Rapid Extraction of Natural Products: Efficient Isolation of Shikimic Acid from Star Anise

被引：69

作者：

Just, Jeremy ^{[1
]}

Deans, Bianca J. ^{[1
]}

Olivier, Wesley J. ^{[1
]}

Paull, Brett ^{[1
,2
]}

Bissember, Alex C. ^{[1
]}

Smith, Jason A. ^{[1
]}

机构：

[1] Univ Tasmania, Sch Phys Sci Chem, Hobart, Tas 7001, Australia

[2] Univ Tasmania, ACROSS, Hobart, Tas 7001, Australia

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 10期

关键词：

HOT-WATER EXTRACTION; PLASMODIUM-FALCIPARUM; (-)-SHIKIMIC ACID; PATHWAY; BIOSYNTHESIS; DERIVATIVES; TAMIFLU; ANALOGS; METABOLITES; ACCESS;

D O I：

10.1021/acs.orglett.5b00936

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

A new, practical, rapid, and high-yielding process for the pressurized hot water extraction (PHWE) of multigram quantities of shikimic acid from star anise (Illicium verum) using an unmodified household espresso machine has been developed. This operationally simple and inexpensive method enables the efficient and straightforward isolation of shikimic acid and the facile preparation of a range of its synthetic derivatives.

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收藏

页码：2428 / 2430

页数：3

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