Implicating PARP and NAD+ depletion in type I diabetes

被引：36

作者：

Charron, MJ

Bonner-Weir, S

机构：

[1] Yeshiva Univ Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA

[2] Harvard Univ, Sch Med, Joslin Diabet Ctr, Div Res, Boston, MA 02215 USA

来源：

NATURE MEDICINE | 1999年 / 5卷 / 03期

关键词：

D O I：

10.1038/6479

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mice deficient in the PARP DNA repair enzyme are refractory to toxin-induced death of pancreatic beta cells and do not become diabetic (pages 314–319).

引用

页码：269 / 270

页数：2

共 10 条

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