Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction

被引：38

作者：

Dominguez-Rodriguez, A

Abreu-Gonzalez, P

Garcia-Gonzalez, M

Ferrer, J

Vargas, M

机构：

[1] Hosp Univ Canarias, Dept Cardiol, Coronary Care Unit, E-38320 Tenerife, Spain

[2] Univ La Laguna, Sch Med, Dept Physiol, E-38207 San Cristobal la Laguna, Spain

来源：

CLINICAL BIOCHEMISTRY | 2005年 / 38卷 / 02期

关键词：

acute myocardial infarction; PAPP-A; acute coronary syndromes; ELISA;

D O I：

10.1016/j.clinbiochem.2004.10.015

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objective: The purpose of this study was to assess whether serum levels of pregnancy-associated plasma protein A (PAPP-A) are elevated early in patients with acute myocardial infarction (AMI). Design and methods: We measured serum levels of PAPP-A in 80 patients with AMI and in 80 age-matched healthy control subjects. The mean (+/- SEM) time from onset of symptoms to blood sampling was 6.3 +/- 2.8 h in the group with AMI. Results: The PAPP-A levels did not differ between the control group and the AMI group (1.24 +/- 0.07 vs. 1.29 +/- 0.02 mIU/l; P = 0.54). Conclusions: Measurement of serum PAPP-A does not seem to be a useful early marker for AMI. (C) 2004 The Canadian Society of Clinical Chemists. All rights reserved.

引用

页码：180 / 182

页数：3

共 9 条

[1] Pregnancy-associated plasma protein a as a marker of acute coronary syndromes [J].