Catalysis-based total synthesis of latrunculin B

被引：127

作者：

Fürstner, A ^{[1
]}

De Souza, D ^{[1
]}

Parra-Rapado, L ^{[1
]}

Jensen, JT ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 43期

关键词：

alkynes; cross-coupling; macrocycles; metathesis; natural products;

D O I：

10.1002/anie.200352413

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The highly selective actin-binding latrunculins (e.g. 1) play a prominent role as probe molecules in chemical biology. A highly concise, productive, and inherently flexible approach to 1 illustrates the excellent profile and use of metal-catalyzed C-C bond formations.

引用

页码：5358 / 5360

页数：3

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