Osteomyelitis and the role of biofilms in chronic infection

被引:286
作者
Brady, Rebecca A. [2 ]
Leid, Jeff G. [3 ]
Calhoun, Jason H. [4 ]
Costerton, J. William [5 ]
Shirtliff, Mark E. [1 ,2 ]
机构
[1] Univ Maryland, Dept Biomed Sci, Sch Dent, Baltimore, MD 21201 USA
[2] Univ Maryland, Dept Microbiol & Immunol, Sch Med, Baltimore, MD 21201 USA
[3] No Arizona Univ, Dept Biol Sci, Flagstaff, AZ 86011 USA
[4] Univ Missouri, Dept Orthopaed Surg, Columbia, MO USA
[5] Univ So Calif, Sch Dent, Ctr Biofilms, Los Angeles, CA 90089 USA
来源
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2008年 / 52卷 / 01期
关键词
osteomyelitis; biofilm; Staphylococcus aureus;
D O I
10.1111/j.1574-695X.2007.00357.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Understanding the mechanisms implicated in the initial attachment, development, and maturation of a biofilm phenotype are of tremendous importance for their effect on the medical, industrial, and public health arenas. This review explores the current understanding of the nature of biofilms and the impact that molecular interactions between the bacteria themselves, as well as between bacteria and the host, may have on biofilm development and phenotype using the nonmotile Gram-positive coccus, Staphylococcus aureus, as an example.
引用
收藏
页码:13 / 22
页数:10
相关论文
共 94 条
[61]   A MECHANISM FOR THE AMELIORATION BY HYPERBARIC-OXYGEN OF EXPERIMENTAL STAPHYLOCOCCAL OSTEOMYELITIS IN RABBITS [J].
MADER, JT ;
BROWN, GI ;
GUCKIAN, JC ;
WELLS, CH ;
REINARZ, JA .
JOURNAL OF INFECTIOUS DISEASES, 1980, 142 (06) :915-922
[62]   Comparative opsonic and protective activities of Staphylococcus aureus conjugate vaccines containing native or deacetylated staphylococcal poly-N-acetyl-β-(1-6)-glucosamine [J].
Maira-Litrán, T ;
Kropec, A ;
Goldmann, DA ;
Pier, GB .
INFECTION AND IMMUNITY, 2005, 73 (10) :6752-6762
[63]   Immunochemical properties of the staphylococcal poly-N-acetylglucosamine surface polysaccharide [J].
Maira-Litrán, T ;
Kropec, A ;
Abeygunawardana, C ;
Joyce, J ;
Mark, G ;
Goldmann, DA ;
Pier, GB .
INFECTION AND IMMUNITY, 2002, 70 (08) :4433-4440
[64]   Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen [J].
McKenney, D ;
Pouliot, KL ;
Wang, Y ;
Murthy, V ;
Ulrich, M ;
Döring, G ;
Lee, JC ;
Goldmann, DA ;
Pier, GB .
SCIENCE, 1999, 284 (5419) :1523-1527
[65]  
MORRISSY RT, 1989, J PEDIATR ORTHOPED, V9, P447
[66]   The σB regulon influences internalization of Staphylococcus aureus by osteoblasts [J].
Nair, SP ;
Bischoff, M ;
Senn, MM ;
Berger-Bächi, B .
INFECTION AND IMMUNITY, 2003, 71 (07) :4167-4170
[67]   Isolation and characterization of a sigB deletion mutant of Staphylococcus aureus [J].
Nicholas, RO ;
Li, T ;
McDevitt, D ;
Marra, A ;
Sucoloski, S ;
Demarsh, PL ;
Gentry, DR .
INFECTION AND IMMUNITY, 1999, 67 (07) :3667-3669
[68]   Characterization of coagulase-negative staphylococci isolated from patients with infected hip prostheses:: use of phenotypic and genotypic analyses, including tests for the presence of the ica operon [J].
Nilsdotter-Augustinsson, A. ;
Koskela, A. ;
Oehman, L. ;
Soederquist, B. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2007, 26 (04) :255-265
[69]   Autoinduction and signal transduction in the regulation of staphylococcal virulence [J].
Novick, RP .
MOLECULAR MICROBIOLOGY, 2003, 48 (06) :1429-1449
[70]   Association between methicillin susceptibility and biofilm regulation in Staphylococcus aureus isolates from device-related infections [J].
O'Neill, Eoghan ;
Pozzi, Clarissa ;
Houston, Patrick ;
Smyth, Davida ;
Humphreys, Hilary ;
Robinson, D. Ashley ;
O'Gara, James P. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (05) :1379-1388