Mycophenolate mofetil: A safe and promising immunosuppressant in neuromuscular diseases

被引:166
作者
Chaudhry, V [1 ]
Cornblath, DR [1 ]
Griffin, JW [1 ]
O'Brien, R [1 ]
Drachman, DB [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA
关键词
D O I
10.1212/WNL.56.1.94
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors report the use mycophenolate mofetil (MM) in the treatment of neuromuscular diseases. Thirty-eight patients (32 with MG, three with inflammatory myopathy, and three with chronic acquired demyelinating neuropathy) were treated with MM for an average duration of 12 months. All patients tolerated MM without major side effects. Twenty-four patients improved either in their functional status or in their ability to reduce corticosteroid dose. Mean time to improvement was 5 months.
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页码:94 / 96
页数:3
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