Potential for metabolic engineering of resveratrol biosynthesis

被引：86

作者：

Halls, Coralie ^{[1
]}

Yu, Oliver ^{[1
]}

机构：

[1] Donald Danforth Plant Sci Ctr, St Louis, MO 63132 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2008年 / 26卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/j.tibtech.2007.11.002

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Resveratrol, an interesting plant phenolic compound, is found in red wine but is not widely distributed in other common food sources. Health benefits of resveratrol include prevention of cardiovascular diseases and cancers, and - as discovered more recently - promotion of longevity in several animal systems. The pathway and enzymes for resveratrol biosynthesis are well characterized. Furthermore, metabolic engineering of this compound has been achieved in plants, microbes and animals. This review attempts to summarize current understanding of resveratrol pathway-engineering in various systems, to outline the challenges in commercial applications and to identify future opportunities for resveratrol bioengineering.

引用

页码：77 / 81

页数：5

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