MHC multimer technology: current status and future prospects

被引：52

作者：

Bakker, AH ^{[1
]}

Schumacher, TNM ^{[1
]}

机构：

[1] Netherlands Canc Inst, Div Immunol, NL-1066 CX Amsterdam, Netherlands

来源：

CURRENT OPINION IN IMMUNOLOGY | 2005年 / 17卷 / 04期

关键词：

D O I：

10.1016/j.coi.2005.06.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The detection of antigen-specific T cell responses by MHC multimer staining is rapidly becoming one of the core immunological techniques, and the technology to produce MHC multimers has been optimized substantially in recent years. Furthermore, recent work demonstrates the potential of high-throughput detection of T cell responses and suggests that manipulation of T cell responses through the use of multimeric MHC reagents is also feasible.

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收藏

页码：428 / 433

页数：6

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