Constituents from leaves of Apocynum venetum L.

被引：65

作者：

Kamata, Kazuaki ^{[1
]}

Seo, Shujiro ^{[1
]}

Nakajima, Jun-Ichiro ^{[1
]}

机构：

[1] Tokiwa Phytochem Co Ltd, Chiba 2850801, Japan

来源：

JOURNAL OF NATURAL MEDICINES | 2008年 / 62卷 / 02期

关键词：

Apocynum venetum; apocynaceae; LC-MS; NMR; malonated flavonol glycoside; antioxidant;

D O I：

10.1007/s11418-007-0202-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An analysis using HPLC-MS revealed that an extract from dried leaves of Apocynum venetum L. contained more than 15 kinds of phenolic constituents. Two malonated flavonol glycosides were further isolated, and their structures were determined to be quercetin 3-O-(6''-O-malonyl)-beta-D-glucoside (1) and quercetin 3-O-(6''-O-malonyl)-beta-D-galactoside (2) by NMR spectroscopic analysis. This is the first report describing the isolation of these malonated flavonol glycosides from A. venetum L. Both glycosides showed strong scavenging activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical.

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页码：160 / 163

页数：4

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