Apoptosis - Life and death in a FLASH

被引:19
作者
Medema, JP [1 ]
机构
[1] Leiden State Univ, Med Ctr, Dept Immunohaematol, NL-2333 AA Leiden, Netherlands
关键词
D O I
10.1038/19638
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
There are many similarities between nematodes and mammals in the pathways that lead to programmed cell death. There are also differences, and one of these is now highlighted -- it seems that mammals have an extra level of complexity. A protein called FLASH has been shown to modulate the activity of a killer protease (caspase), and even its existence was completely unexpected.
引用
收藏
页码:756 / 757
页数:2
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