机构:
Leiden State Univ, Med Ctr, Dept Immunohaematol, NL-2333 AA Leiden, NetherlandsLeiden State Univ, Med Ctr, Dept Immunohaematol, NL-2333 AA Leiden, Netherlands
Medema, JP
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机构:
[1] Leiden State Univ, Med Ctr, Dept Immunohaematol, NL-2333 AA Leiden, Netherlands
There are many similarities between nematodes and mammals in the pathways that lead to programmed cell death. There are also differences, and one of these is now highlighted -- it seems that mammals have an extra level of complexity. A protein called FLASH has been shown to modulate the activity of a killer protease (caspase), and even its existence was completely unexpected.