Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)

被引：92

作者：

Kim, SH ^{[1
]}

Pudzianowski, AT ^{[1
]}

Leavitt, KJ ^{[1
]}

Barbosa, J ^{[1
]}

McDonnell, PA ^{[1
]}

Metzler, WJ ^{[1
]}

Rankin, BM ^{[1
]}

Liu, R ^{[1
]}

Vaccaro, W ^{[1
]}

Pitts, W ^{[1
]}

机构：

[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Princeton, NJ 08560 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 04期

关键词：

MMP-13; inhibition; barbituric acid; structure-based design;

D O I：

10.1016/j.bmcl.2004.12.016

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

引用

页码：1101 / 1106

页数：6

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