Iodine monochloride/silver trifluoromethanesulfonate (ICl/AgOTf) as a convenient promoter system for O-glycoside synthesis

被引：34

作者：

Ercegovic, T ^{[1
]}

Meijer, A ^{[1
]}

Magnusson, G ^{[1
]}

Ellervik, U ^{[1
]}

机构：

[1] Lund Univ, Ctr Chem & Chem Engn, SE-22100 Lund, Sweden

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 06期

关键词：

D O I：

10.1021/ol015547c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The novel promoter system iodine monochloride/silver trifluoromethanesulfonate (ICI/AgOTf) was evaluated with various thioglycoside donors and saccharide accepters, and O-glycosides were obtained in 46-82% yield. Several practical advantages of the ICI/AgOTf system over known promoter systems were observed, such as convenient handling of the reagents and absence of byproducts related to N-succinimide.

引用

页码：913 / 915

页数：3

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