The art and design of genetic screens: maize

被引：62

作者：

Candela, Hector ^{[1
]}

Hake, Sarah ^{[1
]}

机构：

[1] Ctr Plant Gene Express, Albany, CA 94710 USA

来源：

NATURE REVIEWS GENETICS | 2008年 / 9卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1038/nrg2291

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Maize (Zea mays) is an excellent model for basic research. Genetic screens have informed our understanding of developmental processes, meiosis, epigenetics and biochemical pathways-not only in maize but also in other cereal crops. We discuss the forward and reverse genetic screens that are possible in this organism, and emphasize the available tools. Screens exploit the well-studied behaviour of transposon systems, and the distinctive chromosomes allow an integration of cytogenetics into mutagenesis screens and analyses. The imminent completion of the maize genome sequence provides the essential resource to move seamlessly from gene to phenotype and back.

引用

页码：192 / 203

页数：12

共 117 条

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[2] An RNA-dependent RNA polymerase is required for paramutation in maize [J].