Synthesis and molecular structure of heterocyclic Troger's bases derived from C-amino heterocycles

被引：37

作者：

Cudero, J

Pardo, C

Ramos, M

GutierrezPuebla, E

Monge, A

Elguero, J

机构：

[1] UNIV COMPLUTENSE MADRID, FAC QUIM, DEPT QUIM ORGAN 1, E-28040 MADRID, SPAIN

[2] CSIC, INST CIENCIA MAT, LAB DIFRACC RAYOS 10, E-28040 MADRID, SPAIN

[3] CSIC, INST QUIM MED, E-28006 MADRID, SPAIN

来源：

TETRAHEDRON | 1997年 / 53卷 / 06期

关键词：

D O I：

10.1016/S0040-4020(96)01125-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fourteen amino heterocycles were allowed to react in the different experimental conditions of formation of Troger's bases. Amino-azoles and -benzazoles yielded the corresponding Troger's bases while amino-azines and -benzazines failed to react The exception was 6-aminoquinoline which yielded the corresponding Troger's base. When there are two positions of cyclisation the reaction is always regioselective. Troger's base analogues with pentagonal aromatic frameworks, 6b and 7b, have been synthesized for the first time and the X-ray molecular structure of 7b has been determined. (C) 1997, Elsevier Science Ltd.

引用

页码：2233 / 2240

页数：8

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[1] CHEMISTRY OF SYNTHETIC RECEPTORS AND FUNCTIONAL-GROUP ARRAYS .10. ORDERLY FUNCTIONAL-GROUP DYADS - RECOGNITION OF BIOTIN AND ADENINE-DERIVATIVES BY A NEW SYNTHETIC HOST [J].