Evaluation of commercial assay detecting specific immunoglobulin G in oral fluid for determining measles immunity in vaccinees

被引：16

作者：

Kremer, JR

Muller, CP

机构：

[1] Lab Natl Sante, Inst Immunol, L-1011 Luxembourg, Luxembourg

[2] Lab Natl Sante, WHO Collaborat Ctr Measles, L-1011 Luxembourg, Luxembourg

[3] Lab Natl Sante, WHO European Reg Reference Lab Measles & Rubella, L-1011 Luxembourg, Luxembourg

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2005年 / 12卷 / 05期

关键词：

D O I：

10.1128/CDLI.12.5.668-670.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A commercial assay for detection of measles immunoglobulin G (IgG) in oral fluid was evaluated in a highly vaccinated cohort using serum IgG as gold standard. In contrast to previous studies from cohorts protected by natural immunity, antibody prevalence was significantly underestimated (-7.4%; confidence interval: -1.5 to -13.2%; P = 0.01) due to a reduced sensitivity when antibody levels were low.

引用

页码：668 / 670

页数：3

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