Application of measurements of transepithelial electrical resistance of intestinal epithelial cell monolayers to evaluate probiotic activity

被引：97

作者：

Klingberg, TD

Pedersen, MH

Cencic, A

Budde, BB

机构：

[1] Royal Vet & Agr Univ, Dept Food Sci, DK-1958 Frederiksberg, Denmark

[2] Univ Maribor, Fac Agr, SLO-2000 Maribor, Slovenia

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 11期

关键词：

D O I：

10.1128/AEM.71.11.7528-7530.2005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Among five potentially probiotic lactobacilli investigated, Lactobacillus plantarum MF1298 and Lactobacillus salivarius DC5 showed the highest increase in the transepithelial electrical resistance (TER) of polarized monolayers of Caco-2 cells, and this increase was shown to be dose dependent. Furthermore, preincubation with MF1298 attenuated a decrease in TER induced by Listeria monocytogenes.

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页码：7528 / 7530

页数：3

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