Epidemiological studies of human and animal Salmonella -: Typhimurium DT104 and DT104b isolates in Ireland

被引：27

作者：

Murphy, TM ^{[1
]}

McNamara, E

Hill, M

Rooney, N

Barry, J

Egan, J

O'Connell, A

O'Loughlin, J

McFaddyen, S

机构：

[1] Cent Vet Lab, Dept Agr, Dublin 15, Ireland

[2] Cherry Orchard Hosp, Publ Hlth Lab, Dublin 10, Ireland

[3] Dublin City Univ, Fac Sci, Dept Biotechnol, Dublin 9, Ireland

[4] Reg Vet Lab, Kilkenny, Ireland

[5] Reg Vet Lab, Cork 4, Ireland

[6] Reg Vet Lab, Limerick, Ireland

[7] Reg Vet Lab, Doonally, Co Sligo, Ireland

来源：

EPIDEMIOLOGY AND INFECTION | 2001年 / 126卷 / 01期

关键词：

D O I：

10.1017/S0950268801005143

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A total of 122 human and animal Salmonella Typhimurium DT104 isolates and 6 epidemiologically related DT104b isolates from human and animal products were analysed by pulsed-held gel electrophoresis (PFGE). Genomic DNA was subjected to macrorestriction with three enzymes, SpeI, SfiI and XbaI. A total of 14 restriction fragment length polymorphism (RFLP) profiles were identified when the PFGE patterns from the three enzymes were combined. The majority of isolates (81.2 %) exhibited the same RFLP profile. Six animal DT104 isolates, susceptible to enrofloxacin and resistant to naladixic acid, were identified from the antibiotic susceptibility test. Four of these isolates had a different PFGE profile from the common RFLP. In addition, 4 of the 6 isolates were geographically clustered in one region. It was concluded that there was one predominant strain of S. Typhimurium DT104 in Ireland and that the potential and selection pressures for emergence of fluoroquinolone-resistant isolates were present.

引用

页码：3 / 9

页数：7

共 26 条

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[Anonymous], 1991, J Antimicrob Chemother, V27 Suppl D, P1

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