Insulin action and insulin resistance: Diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system

被引：120

作者：

Hunter, SJ

Garvey, WT ^{[1
]}

机构：

[1] Med Univ S Carolina, Dept Med, Charleston, SC 29425 USA

[2] Ralph H Johnson Vet Affairs Med Ctr, Charleston, SC USA

来源：

AMERICAN JOURNAL OF MEDICINE | 1998年 / 105卷 / 04期

关键词：

D O I：

10.1016/S0002-9343(98)00300-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Insulin resistance is a primary abnormality in the evolution of type 2 diabetes and is associated with Syndrome X, a cluster of risk factors predisposing to cardiovascular disease. In the polycystic ovary syndrome, insulin resistance may lead to hyperandrogenism; troglitazone, an insulin sensitizer, corrects abnormalities in the pituitary/gonadal axis in these patients.

引用

收藏

页码：331 / 345

页数：15

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