Conserved and distinct aspects of the avian Toll-like receptor (TLR) system: implications for transmission and control of bird-borne zoonoses

被引：60

作者：

Boyd, A. ^{[1
]}

Philbin, V. J. ^{[1
]}

Smith, A. L. ^{[1
]}

机构：

[1] Inst Anim Hlth, Newbury RG20 7NN, Berks, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2007年 / 35卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

avian Toll-like receptor system; chicken Toll-like receptor; comparative immunology; Toll-like receptor (TLR); transmission of infection; zoonosis;

D O I：

10.1042/BST0351504

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This mini-review focuses on recent research with avian TLRs (Toll-like receptors), highlighting shared and distinct features compared with the more intensively studied mammalian TLR. These include the avian TLR repertoire and the response to various agonists. studies with avian TLR can be applied to development of new approaches to control diseases of birds and is especially relevant to bird-borne zoonoses including avian influenza, Salmonella and Campylobacter.

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收藏

页码：1504 / 1507

页数：4

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