Mechanical properties of calcium phosphate scaffolds fabricated by robocasting

被引：243

作者：

Miranda, Pedro ^{[1
]}

Pajares, Antonia ^{[2
]}

Saiz, Eduardo ^{[3
]}

Tomsia, Antoni P. ^{[3
]}

Guiberteau, Fernando ^{[1
]}

机构：

[1] Univ Extremadura, Dept Elect & Ingn Electromecan, E-06071 Badajoz, Spain

[2] Univ Extremadura, Dept Fis, E-06071 Badajoz, Spain

[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A | 2008年 / 85A卷 / 01期

关键词：

robocasting; hydroxyapatite; beta-tricalcium phosphate; scaffolds; strength;

D O I：

10.1002/jbm.a.31587

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

The mechanical behavior under compressive stresses of beta-tricalcium phosphate (beta-TCP) and hydroxyapatite (HA) scaffolds fabricated by direct-write assembly (robocasting) technique is analyzed. Concentrated colloidal inks prepared from beta-TCP and HA commercial powders were used to fabricate porous structures consisting of a 3D tetragonal mesh of interpenetrating ceramic rods. The compressive strength and elastic modulus of these model scaffolds were determined by uniaxial testing to compare the relative performance of the selected materials. The effect of a 3-week immersion in simulated body fluid (SBF) on the strength of the scaffolds was also analyzed. The results are compared with those reported in the literature for calcium phosphate scaffolds and human bone. The robocast calcium phosphate scaffolds were found to exhibit excellent mechanical performances in terms of strength, especially the HA structures after SBF immersion, indicating a great potential of this type of scaffolds for use in load-bearing bone tissue engineering applications. (c) 2007 Wiley Periodicals, Inc.

引用

页码：218 / 227

页数：10

共 61 条

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