Evaluation of the Gen-Probe PACE 2 assay for the detection of asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees

被引:5
作者
Beltrami, JF
Farley, TA
Hamrick, JT
Cohen, DA
Martin, DH
机构
[1] Tulane Univ, Sch Med, New Orleans, LA 70112 USA
[2] Louisiana Dept Hlth & Hosp, New Orleans, LA USA
[3] Jefferson Parish Correct Ctr, Gretna, LA USA
[4] Louisiana State Univ, Sch Med, New Orleans, LA USA
关键词
D O I
10.1097/00007435-199811000-00001
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: The LET and Gen-Probe PACE 2 assay are used to screen male arrestees for evidence of infection with chlamydia and gonorrhea in the intake/booking area of the Jefferson Parish Correctional Center. Goal of this Study: To determine the accuracy of the GenProbe PACE 2 assay for the detection of asymptomatic infection with Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees, Study Design: From December 1993 to March 1994, 196 arrestees younger than 22 years were screened with the GenProbe PACE 2 assay and McCoy shell vial culture for Chlamydia trachomatis. From April to October 1994, 444 arrestees of all ages were screened with the Gen-Probe PACE 2 assay and standard culture for Neisseria gonorrhoeae, The sensitivity, specificity, and predictive values of the Gen-Probe PACE 2 assay, compared with culture, were calculated with 95% confidence intervals. Results: The Gen-Probe PACE 2 assay compared with culture had a sensitivity, specificity, and positive predictive value for Chlamydia trachomatis of 84%, 99%, and 93% and for Neisseria gonorrhoeae of 54%, 99.5%, and 78%, Conclusion: The Gen-Probe PACE 2 assay is useful for screening young males in this jail setting and is more accurate for detecting Chlamydia trachomatis compared with Neisseria gonorrhoeae.
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页码:501 / 504
页数:4
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