Cross sectional study estimating prevalence of heart failure and left ventricular systolic dysfunction in community patients at risk

被引:40
作者
Nielsen, OW [1 ]
Hilden, J
Larsen, CT
Hansen, JF
机构
[1] Univ Copenhagen Hosp, Dept Cardiovasc, DK-2650 Hvidovre, Denmark
[2] Univ Copenhagen, Panum Inst, Dept Biostat, DK-2100 Copenhagen O, Denmark
[3] Copenhagen Univ Hosp, Dept Cardiovasc Y, DK-2400 Bispebjerg, Denmark
关键词
heart failure; left ventricular systolic dysfunction;
D O I
10.1136/heart.86.2.172
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective-To examine a general practice population to measure the prevalence of signs and symptoms of heart failure (SSHF),and left ventricular systolic dysfunction (LVSD). Design-Cross sectional screening study in three general practices followed by echocardiography. Setting and patients-All patients greater than or equal to 50 years in two general practices and greater than or equal to 40 years in one general practice were screened by case record reviews and questionnaires (n = 2158), to identify subjects with some evidence of heart disease. Among these, subjects were sought who had SSHF (n = 115). Of 357 subjects with evidence of heart disease, 252 were eligible for examination, and 126 underwent further cardiological assessment, including 43 with SSHF Main outcome measures-Prevalence of SSHF as defined by a modified Boston index, LVSD defined as an indirectly measured left ventricular ejection fraction less than or equal to 0.45, and numbers of subjects needing an echocardiogram to detect one case with LVSD. Results-SSHF afflicted 0.5% of quadragenarians and rose to 11.7% of octogenarians. Two thirds were handled in primary care only. At greater than or equal to 50 years of age 6.4% had SSHF, 2.9% had LVSD, and 1.9% (95% confidence interval 1.3% to 2.5%) had both. To detect one case with LVSD in primary care, 14 patients with evidence of heart disease without SSHF and 5.5 patients with SSHF had to be examined. Conclusion-SSHF is extremely prevalent in the community, especially in primary care, but more than two thirds do not have LVSD. The number of subjects with some evidence of heart disease needing an echocardiogram to detect one case of LVSD is 14.
引用
收藏
页码:172 / 178
页数:7
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