Distribution of vacA and cagA genotypes of Helicobacter pylori in Kuwait

被引:35
作者
Al Qabandi, A
Mustafa, AS
Siddique, I
Khajah, AK
Madda, JP
Junaid, TA
机构
[1] Kuwait Univ, Fac Med, Dept Pathol, Safat 13110, Kuwait
[2] Kuwait Univ, Fac Med, Dept Pathol, Safat 13110, Kuwait
[3] Kuwait Univ, Fac Med, Dept Microbiol, Safat 13110, Kuwait
[4] Kuwait Univ, Amiri Hosp, Fac Med, Thuniyan Al Ghanim Gastroenterol Ctr,Dept Med, Kuwait, Kuwait
关键词
Helicobacter pylori; vacA; cagA; genotypes; Kuwait;
D O I
10.1016/j.actatropica.2005.01.004
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
There is considerable geographical variation in the distribution of allelic types of Helicobacter pylori. This first study from Kuwait determined the prevalence of cagA and vacA genotypes among H 7 unselected patients attending a gastroenterology center. We found that whereas vacA s1 and s2 types were equally likely to be present in biopsies obtained from patients of Middle-Eastern origin, African Arabs were predominantly infected with s2 type and South-Asians the s1 type. South Asians most frequently carried the cagA positive genotype with Bangladeshis showing the highest prevalence rate of 87%. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:283 / 288
页数:6
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