Screening of Brazilian basidiomycetes for antimicrobial activity

被引:101
作者
Rosa, LH
Machado, KMG
Jacob, CC
Capelari, M
Rosa, CA
Zani, CL
机构
[1] Fiocruz MS, Ctr Pesquisas Rene Rachou, Lab Quim Prod Nat, BR-30190002 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Microbiol, Belo Horizonte, MG, Brazil
[3] Fundacao Ctr Tecnol Minas Gerais, Santos, SP, Brazil
[4] Univ Catolica Santos, Santos, SP, Brazil
[5] Inst Bot, Secao Micol & Liquenol, Sao Paulo, Brazil
来源
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2003年 / 98卷 / 07期
关键词
antibiotics; bacteria; basidiomycetes; fungi; yeasts;
D O I
10.1590/S0074-02762003000700019
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
A total of 103 isolates of basidiomycetes, representing 84 species front different Brazilian ecosystems, were evaluated for their antifungal and antibacterial activity in a panel of pathogenic and non-pathogenic microorganisms. Tissue plugs of the fruiting bodies were cultivated in liquid media and the whole culture extracted with ethyl acetate. Crude extracts from Agaricus cf. nigrecentulus, Agrocybe perfecta, Climacodon pulcherrimus, Gloeoporus thelephoroides, Hexagonia hydnoides, Irpex lacteus, Leucoagaricus cf. cinereus, Marasmius cf. bellus, Marasmius sp., Nothopanus hygrophanus, Oudemansiella canarii, Pycnoporus sanguineus, Phellinus sp., and Tyromyces duracinus presented significant activity against one or more of the target microorganisms. Eight isolates were active only against bacteria while three inhibited exclusively the growth of fungi. Two extracts presented wide antimicrobial spectrum and were active against both fungi and bacteria. Differences in the bioactivity of extracts obtained front isolates from the same species were observed.
引用
收藏
页码:967 / 974
页数:8
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