A chemical sensor for the liquid-ordered phase

被引:24
作者
Cao, HH [1 ]
Zhang, JB [1 ]
Jing, BW [1 ]
Regen, SL [1 ]
机构
[1] Lehigh Univ, Dept Chem, Bethlehem, PA 18015 USA
关键词
D O I
10.1021/ja0513988
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The mixing properties of exchangeable phospholipids, derived from 1,2-dipalmitoyl-sn-glycero3-phosphoethanolamine and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, with an exchangeable form of cholesterol have been used to monitor the transition from the liquid-disordered to the liquid-ordered phase in cholesterol-containing bilayers, made from 1,2-dipaimitoyl-sn-glycero-3-phosphocholine and 1,2-distearoyl-sn-glycero-3-phosphocholine, respectively.
引用
收藏
页码:8813 / 8816
页数:4
相关论文
共 24 条
[1]   PERCOLATION AND DIFFUSION IN 3-COMPONENT LIPID BILAYERS - EFFECT OF CHOLESTEROL ON AN EQUIMOLAR MIXTURE OF 2 PHOSPHATIDYLCHOLINES [J].
ALMEIDA, PFF ;
VAZ, WLC ;
THOMPSON, TE .
BIOPHYSICAL JOURNAL, 1993, 64 (02) :399-412
[2]   Structure and function of sphingolipid- and cholesterol-rich membrane rafts [J].
Brown, DA ;
London, E .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (23) :17221-17224
[3]   Drug therapy: Mechanisms of actions of inhaled anesthetics [J].
Campagna, JA ;
Miller, KW ;
Forman, SA .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (21) :2110-2124
[4]   The lateral pressure profile in membranes: A physical mechanism of general anesthesia [J].
Cantor, RS .
BIOCHEMISTRY, 1997, 36 (09) :2339-2344
[5]   Unraveling the mystery surrounding cholesterol's condensing effect [J].
Cao, HH ;
Tokutake, N ;
Regen, SL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (52) :16182-16183
[6]   Nearest-neighbor recognition in phospholipid membranes [J].
Davidson, SMK ;
Regen, SL .
CHEMICAL REVIEWS, 1997, 97 (05) :1269-1279
[7]   Partitioning of Thy-1, GM1, and cross-linked phospholipid analogs into lipid rafts reconstituted in supported model membrane monolayers [J].
Dietrich, C ;
Volovyk, ZN ;
Levi, M ;
Thompson, NL ;
Jacobson, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (19) :10642-10647
[8]   The state of lipid rafts: From model membranes to cells [J].
Edidin, M .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2003, 32 :257-283
[9]   EVIDENCE FOR TRANSBILAYER, TAIL-TO-TAIL CHOLESTEROL DIMERS IN DIPALMITOYLGLYCEROPHOSPHOCHOLINE LIPOSOMES [J].
HARRIS, JS ;
EPPS, DE ;
DAVIO, SR ;
KEZDY, FJ .
BIOCHEMISTRY, 1995, 34 (11) :3851-3857
[10]  
IPSEN JH, 1987, BIOCHIM BIOPHYS ACTA, V905, P162